Self-reported discomfort associated with use of different nonoxynol-9 spermicides.

Do spermicides containing nonoxynol-9 prevent sexually transmitted infections? A meta-analysis.

BACKGROUND AND OBJECTIVES There are conflicting opinions on whether to recommend spermicides containing nonoxynol-9 for prevention of sexually transmitted diseases, including human immunodeficiency virus (HIV). GOAL To systematically review and summarize the medical literature on the effect of spermicides containing nonoxynol-9 on prevention of gonorrhea, chlamydial infection, and HIV. STUD...

Iodo-Nonoxynol-9-Derivatives and Methods for Their Use

Are there alternatives to nonoxynol-9 spermicide?

You're certainly not alone in your interest of this method. Spermicide is a popular option for birth control because it is easily accessible, simple to use, and provides added lubrication. Results from recent scientific studies for newer alternatives look promising, but more research is still needed. Some of the new ingredients being studied that may be able to function as spermicide (and provi...

Nonoxynol-9 use, genital ulcers, and HIV infection in a cohort of sex workers.

OBJECTIVES To measure the associations between use of nonoxynol-9 (N-9) and incidence of genital ulcers, and incident ulcers and HIV seroconversion. METHODS In a study of barrier contraceptive use and HIV infection, 273 female sex workers used condoms and 100 mg N-9 suppositories, and recorded sexual activity on coital logs. Genital ulcers were diagnosed clinically at monthly clinic visits. H...

Condoms with nonoxynol-9 (N-9) ? do they increase HIV risk?

Great questions! Here's the scoop on what you heard: according to a four-year study conducted by the Joint United Nations Programme on HIV/AIDS (UNAIDS) [2], women who used nonoxynol-9 (N-9) gel were infected with human immunodeficiency virus (HIV) at a higher rate than those who used a placebo gel. Though N-9 isn?t effective at protecting against HIV and other sexually transmitted infections (...